SSRIs may activate vagus nerve dependent gut-to-brain serotonin signaling. Originally Posted October 6, 2019 Reviewed by Devon Frye When Prozac was introduced in 1987, it made a big splash as the first selective serotonin reuptake inhibitor (SSRI) antidepressant for the treatment of major depressive disorder. Prozac and Sarafem are brand names for a drug called …
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